细胞生物学(厦门大学) 中国大学mooc答案满分完整版章节测试

茎粪纶权渐些尘隆侍涕廊俩瓶


Introduction of Molecular cell biology Cell theory-test

1、 What did Leeuwenhoek do?

答案: Used simple light microscope and saw microorganisms

2、 He discovered that all animals were made of cells, which contributed to the development of the cell theory:

答案: Theodor Schwann

3、 Who was the first person to see cells under the microscope and give them a name?

答案: Robert Hooke

4、 Which of the following is NOT one of the main components of the cell theory?

答案: cells must contain DNA

Culturing and visualizing cells Culturing and visualizing cells-test

1、  The most direct source of monoclonal antibodies are __ cells.

答案: Hybridoma

2、 The fluorescent properties of dyes such as FITC can provide information on the

答案: location of specific proteins.

3、 What factors necessary for growth of animal cells in culture are provided by serum?

答案: growth factors 

4、 What is the advantage of using GFP-tag to visualize specific proteins, instead of staining cells with fluorescent dyes that bind to the target protein?

答案: GFP fusions enable one to track changes in the location of the protein in living cells; staining usually requires fixed cells

5、 Which one cleaves pre-miRNA in the cytoplasm to produce miRNA?

答案: Dicer

6、 A single monoclonal antibody can bind to several different sites on an antigen

答案: 错误

7、 RNAi can be mediated just by introducing the already processed miRNA/siRNA into cells

答案: 正确

8、 _______  degrades mRNAs with sequences complementary to a bound siRNA
答案: RISC

Biomembrane Structure Biomembrane Structure-test

1、 All the following statements describe biomembranes except:

答案:  Some biomembranes have free edges.

2、  The major site of lipid synthesis in eukaryotic cells is the

答案: Endoplasmic reticulum

3、 Phospholipids with short or unsaturated fatty acyl chains

答案: increase membrane fluidity.

4、  The _ are transmembrane proteins.

答案: integral membrane proteins

5、 Glycolipids and glycoproteins are especially abundant in the

答案: plasma membrane

6、 Phosphate containing lipids include all of the following except 

答案: triglyceride

7、 A lipid bilayer is the fundamental structural component of all cell membranes.

答案: 正确

8、 Maintenance of the lipid bilayer in the plasma membrane requires special enzymes and the hydrolysis of ATP.

答案: 错误

9、 The most abundant lipids in cell membranes are ____.
答案: phospholipids

10、 Sugar-containing lipids called ______ are found only in the outer half of the bilayer and their sugar groups are exposed ac the cell surface.
答案: glycolipids

Transmembrane transport of Ions and small molecules

1、 Classes of membrane transport proteins include all of the following except

答案: protein translocons.

2、 The glucose uniporter GLUT1 has a Km of 1.5 mM for D-glucose and 30 mM for D-galactose.  At a concentration of 5 mM for each, what is the rate of glucose transport relative to galactose transport?  The Vmax may be assumed to be the same for both.

答案: 5.5-fold faster

3、 How does uniport transport compare to simple diffusion?

答案: Uniport transport is much faster and more specific than simple diffusion.

4、 Which of the four classes of ATP-powered pumps share overall similarity: several subunits, the same general organization, and a similar function in being H+ transporters?

答案: F-class pumps and V-class pumps

5、 How does inhibition of the Na+/K+ ATPase increase the force of heart muscle contraction?

答案: It increases cytosolic Na+ and therefore decreases Ca2+ export

6、 Channel proteins (such as the voltage-gated Na channel) transport ions much faster than carrier proteins (such as the Na-K pump), but they cannot be coupled to an energy source; therefore, transport mediated by channels is always passive.

答案: 正确

7、 The resting membrane potential of a typical animal cell arises predominantly through the action of the Na-K pump, which in each cycle transfers 3 Na ions out of the cell and 2 K into the cell, leaving an excess of negative charges inside the cell.

答案: 错误

8、  The concentration gradient for a charged solute and the membrane potential constitute the _______ gradient for that solute.
答案: electrochemical

9、 Over expression of the ____ in human cancer cells can make these cells simultaneously resistant to a variety of chemically unrelated cytotoxic drugs that we widely used in cancer chemotherapy.
答案: Multidrug-resistance transport protein

10、 In the epithelial cells of the gut Na+-linked symporters in the apical (absorptive) domain of the plasma membrane and Na+-independent transport proteins in the basolateral domain bring about the _______ of absorbed solutes.
答案: Transcellular transport

Cellular Energetics

1、 Where does glycolysis takes place?

答案: Cytosol

2、 Where is the electron transport chain found in plant cells?

答案: Thylakoid membranes of chloroplasts

3、 Energy released by the electron transport chain is used to pump H+ ions into which location?

答案: Mitochondrial intermembrane space

4、 Inside an active mitochondrion, most electrons follow which pathway?

答案: Citric acid cycle –> NADH –> electron transport chain –> oxygen

5、 Which do the catabolic products of fatty acid breakdown enter into the citric acid cycle?

答案: Acetyl CoA

6、 Brown-fat mitochondria uncouple oxidative phosphorylation to produce____

答案: Heat

7、 During ATP synthesis, protons move “down” their electrochemical gradient through  the F0 complex of ATP synthase

答案: 正确

8、 The outer mitochondrial membrane is derived from the bacterial plasma membrane

答案: 错误

9、 ____ is a lipid soluble molecule that acts to shuttle electrons within the mitochondrial inner membrane
答案: CoQ
分析:Coenzyme Q

10、 The energy released by the passage of electrons along the respiratory chain is stored as an_____ across the inner mitochondrial membrane.
答案: proton motive force
分析:electrochemical gradient

Moving Proteins into Membranes and Organelles

1、 Type I membrane proteins have all of the following properties except

答案: internal signal-anchor sequence

2、  Many peroxisomal matrix proteins are imported as

答案: folded proteins

3、 GPI-anchoring serves a special function, especially in polarized epithelial cells because this modification serves to target proteins to the

答案: Plasma membrane

4、 Glycosylation, a post-translational modification to proteins, occurs in the

答案: ER

5、  Protein sequences for targeting to mitochondria is located at

答案: the N-terminus of the precursor protein.

6、 Mitochondrial signal peptides are amphipathic α helical structures with positively charged amino acid one side and negatively charged amino on the other side.

答案: 错误

7、 In mammalian cells the import of proteins into the ER begins before the polypeptide chain is completely synthesized-that is ,it occurs co-translationally.

答案: 正确

8、 The fate of proteins synthesized in the cytosol depends on their amino acid sequence, which can contain _____ that direct their delivery to locations outside the cytosol.
答案: signal

9、 The _____at which the inner and outer mitochondrial membranes appear to be joined are thought to be the sites at which import into the matrix occurs.
答案: contact site

10、 The signal peptide is guided to the membrane of the ER by at least two components:a ___ ,which binds to the signal peptide in the cytosol, and the _______,which is located in the ER membrane . 
答案: SRP



上方为免费预览版答案,如需购买完整答案,请点击下方红字

点击这里,购买完整版答案


 

点关注,不迷路,微信扫一扫下方二维码

关注我们的公众号:阿布查查  随时查看答案,网课轻松过

细胞生物学(厦门大学) 中国大学mooc答案满分完整版章节测试第1张


为了方便下次阅读,建议在浏览器添加书签收藏本网页

电脑浏览器添加/查看书签方法

1.按键盘的ctrl键+D键,收藏本页面

细胞生物学(厦门大学) 中国大学mooc答案满分完整版章节测试第2张

2.下次如何查看收藏的网页?

点击浏览器右上角-【工具】或者【收藏夹】查看收藏的网页

细胞生物学(厦门大学) 中国大学mooc答案满分完整版章节测试第3张


手机浏览器添加/查看书签方法

一、百度APP添加/查看书签方法

1.点击底部五角星收藏本网页

细胞生物学(厦门大学) 中国大学mooc答案满分完整版章节测试第4张

2.下次如何查看收藏的网页?

点击右上角【┇】-再点击【收藏中心】查看

细胞生物学(厦门大学) 中国大学mooc答案满分完整版章节测试第5张

二、其他手机浏览器添加/查看书签方法

1.点击【设置】-【添加书签】收藏本网页

细胞生物学(厦门大学) 中国大学mooc答案满分完整版章节测试第6张

2.下次如何查看收藏的网页?

点击【设置】-【书签/历史】查看收藏的网页

细胞生物学(厦门大学) 中国大学mooc答案满分完整版章节测试第7张

博拨茎玛星吹弯快憨惋距年丧